When can I take Xanax after taking diflucan

Diflucan and Xanax are drugs that should not be taken together. But before we discuss how long you should wait to take Xanax after taking Diflucan, let’s talk about these drugs and their uses.


What is Xanax?

Xanax is the brand name of the drug alprazolam, which belongs to a class of medications called benzodiazepines.

Alprazolam is commonly prescribed to treat panic disorders, anxiety disorders, and sometimes depression problems.

This drug works by increasing neurotransmitter activities (gamma-aminobutyric acid (GABA)) in the brain.

GABA has a calming effect on the nervous system, therefore, Alprazolam, or Xanax as it’s commonly referred to, is capable of inducing sleep in users.

Alprazolam is a prescription drug, and if abused, it can cause side effects such as dizziness, drowsiness, or confusion.



Diflucan is a brand name for fluconazole and other similar antifungal drugs.

Diflucan is commonly used to prevent or treat various types of fungal infections, including yeast infections of the mouth, throat, esophagus, lungs, bladder, genital area, and blood.

Fluconazole works by stopping the growth of fungi that cause infections and boosting your body’s immune system to destroy the fungus.

Diflucan is available in various forms, including tablets, oral suspensions, and injections, and is typically taken once daily for 1 to 14 days, depending on the type and severity of the infection being treated.

Like benzodiazepines, fluconazole side effects can include dizziness, ataxia, headache, nausea, diarrhea, and stomach upset.

When can I take Xanax after taking diflucan

How Long After I Take Diflucan can I take Xanax?

First, you should never take Xanax and Diflucan together or on the same day. Xanax and Diflucan interaction can raise the concentration and toxicity of alprazolam (Xanax) in your blood.

This can increase blood levels, and cause drowsiness and respiratory problems. Other drugs you should not take with Xanax are sleeping pills or any drug that has a calming effect.

If you want to treat fungal infections and anxiety problems at the same time, it’s advisable to take Diflucan first and take not more than 0.25mg of Xanax after 6 hours. In this way, it’s generally safe and you’re not likely to experience any interaction.

However, it’s always advisable to consult your doctor before taking any benzodiazepine and fluconazole in the same period.



In general, it is not safe to take Xanax while on Diflucan medications, but the timing of when to take these medications is very important to the safety of usage. Also, the dose of Xanax you want to take is another important factor.

Taking 0.50mg of Xanax or more usually triggers the side effects earlier mentioned while 0.25mg of Xanax is generally safe.

It’s also important to note that both Diflucan and Xanax can cause drowsiness, so you may want to avoid driving or a y other activity that requires mental alertness, especially when poor coordination can cause injury.